Description
Gabriel Petre Gorecki, Elena Rusu, Cosmin Moldovan, Daniel Cochior
Introduction. Due to the high incidence, morbidity, mortality and high costs for the health system, sepsis stands out, among other things, by the firm indication of hospitalization in an intensive care unit. Dysfunction of microcirculation plays a central role in the genesis and maintenance of septic syndrome, being a pathophysiological milestone of this syndrome. The possibility of detecting microvascular anomalies in the early stages with the help of videocapilaroscopy opens up new diagnostic and research opportunities.
Material and method. Our multicenter study was conducted on 51 patients, selected from 3 ICU clinics in a period of 1 year (August 2019 – November 2020).
Results. Videocapilaroscopies were performed with a prototype device, recording 357 images of the microcirculation of the oral mucosa in these patients in whom we have already had confirmation of the diagnosis of sepsis, by classical clinical and paraclinical means.
Discussions. The statistical analysis of the essential elements detected by videocapilaroscopy (capillary density, incidence, diameter) corroborated with the clinical and paraclinical elements of the sepsis state path clearly highlights the correlation power of these determinations.
Conclusions. Given the completely non-invasive nature of this imaging method, the very low costs associated with the method, the ease in collecting and interpreting data as well as the results with strong statistical correlation, we can say that it can successfully represent a method of prediction with high reliability and specificity in the early detection of sepsis, regardless of etiology.
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