GOLD STANDARD COMPUTER TOMOGRAPHY IN THE DETECTION OF BRONCHO-PULMONARY NEOPLASM

Description

Costin POPESCU, Liviu MARTIN, Dan Gheorghe MĂLĂESCU, Mihnea Costin TUTA, Mihaela IONESCU, Dănuț GHIȚĂ, Liliana POPESCU, Marian OLARU, Viorel RĂDULESCU, Constantin CALAFETEANU

Lung cancer is the phenotypic consequence of an accumulation of genetic changes in airway epithelial cells that result in unrestrained cellular proliferation.The genetic and molecular changes that typify lung cancer are complex and not yet fully understood. Many epidemiologic studies have demonstrated that some cancers are clustered in families, suggesting that susceptibility to the cancer may be inherited. Lung cancer, however, is most commonly thought of as a cancer that is determined solely by the environment. Certainly, the risks of lung cancer associated with cigarette smoking and in certain occupations, such .as uranium mining and shipbuilding, arewell established. Although lung cancers are frequently detected on chest radiographs, chest radiographs are of limited use in the evaluation and staging of lung cancer. CT is a more sensitive test for lung cancer and is the most widely used imaging investigation to evaluate the primary tumor and the extent of regional intrathoracic and extrathoracic disease. Magnetic resonance imaging (MRI) may provide additional information in selected cases when mediastinal or chest wall invasion is suspected. Positron emission tomography (PET) with 18F-fluorodeoxyglucose (18F-FDG) has become a very useful tool in the staging of lung cancer. It has been found to increase the accuracy of preoperative staging, especially when used in conjunction with CT (PET-CT).

https://doi.org/10.58679/UTM22834