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PSEUDOEPHEDRINE CONTRAINDICATIONS AND APPLICATIONS

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Horia Sebastian ILIESCU, Sabina IONESCU, Camelia PETRESCU

Pseudoephedrine is an active substance found in plants, with concentrated production in China and India, discovered since 1920. The work presents the mechanism of action, indications, contraindications, and conditions of pseudoephedrine, concluding with summaries and references. Prohibited in sports due to its stimulant activity, it is a common nasal decongestant. Its mechanism, similar to adrenaline, makes it useful in allergic rhinitis and sinusitis. During pregnancy and breastfeeding, it poses minimal risks but requires attention. Contraindicated in diabetes, glaucoma, or prostatic hypertrophy, it may exacerbate cardiovascular conditions. Illegally used for methamphetamine, it underscores the need for strict regulation. In conclusion, the therapeutic benefits are evident, but careful monitoring and strict regulation are essential to minimize risks, especially in pregnant and breastfeeding women.

https://doi.org/10.58679/UTM72409

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